I don't know if it counts as comic book, but it's Japanese manga, so I might as well include it.
Jojo's Bizarre Adventure (1987-Present): A generational saga through different periods of times, following the bloodline of the Joestar family. Through different protagonists, different horror genres and diverse characters and clothing, Jojo is certainly a unique franchise, and feels like a Japanese version of Doctor Who.
I'll admit that I followed this franchise at first, due to huge word of mouth on the Internet, but I am certainly glad that I did. It's certainly a difficult thing to describe what it's about, but the appeal of it, is the unique and varied styles it is in, especially since the franchise is split off into multiple parts. From Victorian Gothic Horror, Twin Peaks Murder Mystery, Wild West Odyssey, Italian Mafia Action Drama, there's always something varied about the franchise. And from the different genres, come the different members of the Joestar family, and all of them are endearing and enjoyable, even the weakest ones. From the kind hearted Victorian gentleman of Jonathan Joestar, the Clint Eastwood-like teenage delinquent of Jotaro Kujo, the quirky and likeable high school student of Josuke Higashikata, the abrasive and feisty female of Jolyne Kujo, and others. My favourites being Joseph Joestar, Josuke Higashikata and Jolyne Kujo.
Another aspect is the problem solving is so different to how other action manga handle conflicts. Jojo often handles fight scenes not just by utterly punching the shit out of enemies, there's often a strategic side in defeating bad guys, like a game of chess. And they're so entertaining to watch, even if some are overly bafflingly complex.
And one final point is the art. My word, the art is magnificent. It's all so diverse, and feels like the writer/artist, Araki is constantly evolving, with him taking inspiration from buff action heroes in the 80s like Kurt Russell, Sylvester Stallone, Arnold Schwarzenegger, to the Gucci eccentric fashionable clothing, and utterly insane poses, I'm always captivated by the art. And for the art being so good that it's the only Japanese manga to be constantly featured at the Louvre is an achievement. And the music references are just insane, it's no secret that the author is a huge Western fan, and loves naming characters or powers after either bands or songs, specifically 60s-00s bands and songs. Killer Queen, Steely Dan, Dirty Deeds Done Dirt Cheap, Bad Company, etc. I would have never heard the likes of Enigma, King Crimson or Earth Wind and Fire if it wasn't for the musical references in the franchise.
But yeah, I was pleasantly surprised with Jojo's Bizarre Adventure, considering that I'm not a huge anime/manga enthusiast. It might not be my favourite piece of media, but if it makes sense, it's probably the most fun that I have had experiencing a piece of media, even more than Doctor Who.